2,4-diamino-6-chloropyrimidine Cas 156-83-2

Description

2,4-Diamino-6-chloropyrimidine, also known as 4-Chloro-2,6-diaminopyrimidine, 6-Chloropyrimidine-2,4-diamine or 2,6-Diamino-4-chloropyrimidine, is an important intermediate of Minoxidil. It belongs to the class of pyrimidine derivatives and is characterized by the presence of amino and chloro groups on its molecular structure. It is a white to off-white crystalline powder.

2,4-Diamino-6-chloropyrimidine has various applications in the field of pharmaceuticals and agrochemicals. It is used as an intermediate in the synthesis of various compounds, including pharmaceutical drugs and agrochemicals. It serves as a building block for the preparation of pyrimidine-based compounds with diverse biological activities. Its chemical properties make it suitable for the development of potential drug candidates and crop protection agents.

Features

❶ Chemical Structure: It is a pyrimidine derivative with two amino groups (NH2) and achlorine (Cl) atom attached to the pyrimidine ring.

❷ Solid State: It exists as a crystalline solid at room temperature and is generally stable under normal conditions.

❸ Water Solubility: It exhibits moderate water solubility, meaning it can dissolve to some extent in water.

❹ Chemical Reactivity: It can participate in various chemical reactions due to the presence of reactive amino groups, allowing for the synthesis of different compounds.

❺ Specificity: The chloro substitution at the 6th position of the pyrimidine ring imparts specific properties and reactivity, which can influence its applications in various fields.

❻ Pharmacological Activity: While it is not primarily known for its pharmacological properties, it may exhibit certain biological activities depending on its interaction with specific receptors or targets.

Applications

1. Pharmaceutical Industry

It serves as an important intermediate in the synthesis of pharmaceutical compounds, including the production of drugs such as Minoxidil, which is used to treat hair loss and promote hair growth.

2. Agrochemical Industry

It can be utilized in the production of pesticides and herbicides, contributing to the development of effective crop protection products.

3. Chemical Research

Due to its unique structure and reactivity, 2,4-Diamino-6-chloropyrimidine is employed as a building block or starting material in chemical research and synthesis. It can be further modified or functionalized to create new compounds with desired properties.

4. Laboratory Research

It may find applications in laboratory settings for experimental purposes, such as in the study of chemical reactions or the development of new compounds.

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Specifications

Product Name	2,4-Diamino-6-chloropyrimidine
Cas No.	156-83-2
Molecular Formula	C4H5ClN4
Molecular Weight	144.56
Appearance	White to off-white crystalline powder
Density	1.564
Purity	99% Min
Solubility	Soluble in water. It is more soluble in organic solvents such as ethanol and methanol.
Boiling point	438.3±48.0 °C at 760 mmHg
Melting point	199-202℃
Flash point	218.9 °C
Vapour	0.0±1.1 mmHg at 25°C
Refractive index	1.702
SMILES	ClC=1C=C(N)N=C(N)N1
InChI Key	InChIKey=QJIUMVUZDYPQRT-UHFFFAOYSA-N